Acute myeloid leukemia following radioactive iodine therapy for papillary carcinoma of the thyroid.

نویسندگان

  • Jain Ankit
  • Premalata C S
  • Saini K S
  • Bapsy P P
  • Sajeevan K V
  • Tejinder Singh
  • Ullas Batra
  • Babu Govind
  • Lokanatha Dasappa
  • Suresh Atilli
  • Permeshwar R
چکیده

Radioactive iodine (RAI) therapy plays an important role in the management of thyroid malignancies. Leukemia is a very rare complication of radioactive therapy. There are very few case reports with doses below 100 mCi causing leukemia. We report a case of papillary carcinoma of the thyroid treated with 80 mCi RAI who later developed acute myeloid leukemia. Thus, all patients with thyroid carcinoma treated with RAI should undergo periodic hematological examinations irrespective of RAI dose.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

An Unusual Case Report: Occurrence of Renal Cell Carcinoma, Basal Cell Carcinoma and Chronic Lymphocytic Leukemia in a Case of Papillary Thyroid Carcinoma Treated with Radioactive Iodine

The standard therapy for thyroid cancer is total or near total thyroidectomy, followed by the administration of radioactive iodine for remnant ablation or residual disease. Patients with radioiodine therapy are predisposed to second malignant neoplasms in organs such as central nervous system (CNS), breast, prostate, kidney, bone marrow, salivary gland, and digestive tract. Exposure to carcinog...

متن کامل

Chronic myeloid leukemia after treatment with 131 for thyroid carcinoma.

A 27-year-old male developed Philadelphia chromosome-positive chronic myeloid leukemia (CML) 13 years after a first dose of radioiodine (131I) therapy for papillary thyroid carcinoma. He had received a cumulative 131I dose of 670 mCi, in 8 divided doses over 8 years, up to April 1998, for ablation of 131I avid tissues over the anterior neck region. The leukemogenic potential of radioactive iodi...

متن کامل

Hyperparathyroidism Two Years after Radioactive Iodine Therapy in an Adolescent Male

Primary hyperparathyroidism is a very rare complication following radioactive iodine therapy. There is typically a latency period of more than a decade following radiation exposure and, therefore, it is observed almost exclusively in adults. Consequently, pediatricians are not aware of the association. We present a case of primary hyperparathyroidism due to a solitary parathyroid adenoma occurr...

متن کامل

Radiation dose of caregivers could be reduced in thyroid carcinoma patients requiring high dose of radioactive iodine: A case report

Undesired radiation exposure to caregivers is an important problem in radioiodine therapy in thyroid carcinoma patients, especially when patient is non-ambulatory. Special precautions are needed to keep the exposure to caregivers low when higher dose of radioiodine is necessary. Here we present a case-report of a 74-year old male patient with papillary thyroid carcinoma with local invasion and...

متن کامل

Multiple non-malignant iodine uptake in a 131I whole body scan of a patient with papillary thyroid carcinoma: Importance of SPECT/CT

After thyroidectomy in papillary thyroid carcinoma (PTC) patients, whole body radioiodine scan (WBIS) is necessary for localization of any abnormal radioiodine avid lesions. However false-positive radioiodine uptake in WBIS can be problematic. We report a 32 years old female patient with PTC. After thyroidectomy and radioiodine therapy WBIS was performed. In her post therapy WBIS, there were zo...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Turkish journal of haematology : official journal of Turkish Society of Haematology

دوره 26 2  شماره 

صفحات  -

تاریخ انتشار 2009